Ozempic and asthma: what the 2026 study found and what it did not
Updated Sep 27, 2026. Numbers in brackets link to the source each fact comes from.
Semaglutide, the medicine in Ozempic and Wegovy, is not approved to treat asthma. The headline finding, nearly 40% fewer asthma attacks, comes from an analysis of UK health records presented at a medical congress, and its lead researcher says it needs confirmation in clinical trials before it changes anyone’s treatment [3] [4].
What was presented in September 2026
The European Respiratory Society announced the results on September 8, 2026, at its congress in Barcelona [6]. The work was led by Chloe Bloom of Imperial College London [15].
- Design. Researchers used UK electronic medical records to run four parallel studies. The four groups ranged from 20,000 to 22,000 people, and each compared new GLP-1 users with new users of a sulfonylurea, an older diabetes drug [2].
- Result. Among people with asthma or COPD, attacks and flare-ups were less common in the GLP-1 groups than in comparable sulfonylurea groups. The strongest link was for semaglutide in people with asthma, about 40% fewer asthma attacks, and semaglutide was also linked to about 20% fewer COPD flare-ups [3].
- Why records, not a trial. The lead researcher, Chloe Bloom, notes that asthma and COPD have never been measured as outcomes in GLP-1 drug trials [5].
The society’s own headline says semaglutide “can reduce” asthma attacks by up to 40 per cent [1]. The study behind it compared records of people who were prescribed different medicines. It did not assign medicines at random, so it can show an association, not that semaglutide caused the drop.
As of this page’s update date, the 2026 analysis did not appear in our PubMed searches as a full paper. The society’s release links to the abstract as a downloaded file, which we did not open, so the numbers above are the ones the society published.
The earlier study, which is on PubMed
The same Imperial College team published a related study in JAMA Internal Medicine in 2025 [7]. It used UK primary care records linked to hospital and death data covering 2004 to 2020 [8], and it looked only at adults with asthma and type 2 diabetes who were starting metformin [9].
- Out of more than 2 million adults with asthma in the records, 4,278 were included in the main within-person analysis [10].
- Metformin was linked to fewer asthma attacks, and GLP-1 medicines were the only add-on diabetes drugs linked to a further drop, with an incidence rate ratio of 0.60 [11] [12].
This was also an observational study. It did not test semaglutide on its own against a placebo, and it did not include people with asthma who do not have type 2 diabetes.
What the research does not show
- It does not show that semaglutide prevents asthma attacks, only that people who took it had fewer of them in the records [4].
- It does not settle why. The 2025 paper reported that the link did not appear to run through blood sugar control or weight loss [18], but a records study cannot prove a mechanism.
- It does not cover people without diabetes or obesity who might want semaglutide only for their lungs. Bloom says people with asthma or COPD should not start a GLP-1 for their lung condition outside current prescribing guidance [4].
What the labels say
Ozempic is approved for adults with type 2 diabetes: to improve blood sugar control, and to lower certain heart and kidney risks in that group [13] [16] [17]. Wegovy’s approved uses include weight management and lowering the risk of heart attack, stroke and cardiovascular death in adults with heart disease and obesity or overweight [14]. Neither label mentions asthma, so a prescription written for asthma alone would be off-label. See what each GLP-1 is approved for.
If you have asthma and already qualify for a GLP-1 because of diabetes or weight, you can bring this research to your prescriber. Keep using your asthma medicines as prescribed: these studies compared GLP-1 medicines with another diabetes drug, not with asthma treatment [2].
Sources
The diabetes and weight loss injection semaglutide can reduce asthma attacks by up to 40 per cent according to research presented at the European Respiratory Society (ERS) Congress in Barcelona, Spain
ersnet.org, read Sep 27, 2026.Using UK electronic medical records, the researchers conducted four parallel studies that each looked at between 20,000 and 22,000 people who started taking any type of GLP-1 treatment or another type of diabetes medication called sulfonylureas.
ersnet.org, read Sep 27, 2026.The effect was strongest with semaglutide especially in people with asthma, where use of semaglutide appears to be associated with nearly 40% reduction in asthma attacks. Semaglutide also led to a 20% reduction in COPD flare ups.
ersnet.org, read Sep 27, 2026.The findings from this study are encouraging, but they should not change treatment decisions on their own. People with asthma or COPD should not start GLP-1 receptor agonists specifically for their lung condition outside current prescribing guidance. While the findings suggest that some people taking GLP-1 receptor agonists may experience fewer respiratory attacks, this needs confirmation in clinical trials.
ersnet.org, read Sep 27, 2026.However, asthma and COPD outcomes have not been included as outcomes in GLP-1 drug trials.
ersnet.org, read Sep 27, 2026.Tuesday, 8 September, 2026 – Barcelona, Spain.
ersnet.org, read Sep 27, 2026.Bloom CI(1). Author information: (1)National Heart and Lung Institute, Imperial College London, London, England.
pubmed.ncbi.nlm.nih.gov, read Sep 27, 2026.The study used data from the UK Clinical Practice Research Datalink (CPRD) Aurum linked hospital admissions and mortality data from 2004 to 2020.
pubmed.ncbi.nlm.nih.gov, read Sep 27, 2026.Eligible participants were new users of metformin with type 2 diabetes.
pubmed.ncbi.nlm.nih.gov, read Sep 27, 2026.Of more than 2 million adults with asthma, 4278 patients (2617 women [61.2%]; mean [SD] age, 52.9 [13.6] years) were identified for the SCCS and 8424 patients
pubmed.ncbi.nlm.nih.gov, read Sep 27, 2026.The only add-on antidiabetic medication to have an additive association was GLP-1RA (SCCS: IRR, 0.60; 95% CI, 0.49-0.73).
pubmed.ncbi.nlm.nih.gov, read Sep 27, 2026.The results of this cohort study suggest that metformin was associated with a lower rate of asthma attacks, with further reductions with the use of GLP-1RA.
pubmed.ncbi.nlm.nih.gov, read Sep 27, 2026.as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus.
dailymed.nlm.nih.gov, read Sep 27, 2026.to reduce the risk of major adverse cardiovascular (CV) events (CV death, non-fatal myocardial infarction, or non-fatal stroke) in adults with established CV disease and either obesity or overweight.
dailymed.nlm.nih.gov, read Sep 27, 2026.The study was led by Professor Chloe Bloom, Clinical Associate Professor in Respiratory Epidemiology at the National Heart & Lung Institute, Imperial College London, UK, and presented by Dr Bohee Lee.
ersnet.org, read Sep 27, 2026.to reduce the risk of major adverse cardiovascular events (cardiovascular death, non-fatal myocardial infarction or non-fatal stroke) in adults with type 2 diabetes mellitus and established cardiovascular disease.
dailymed.nlm.nih.gov, read Sep 27, 2026.to reduce the risk of sustained eGFR decline, end-stage kidney disease, and cardiovascular death in adults with type 2 diabetes mellitus and chronic kidney disease.
dailymed.nlm.nih.gov, read Sep 27, 2026.This appeared to be associated with mechanisms other than through glycemic control or weight loss and occurred across asthma phenotypes.
pubmed.ncbi.nlm.nih.gov, read Sep 27, 2026.
This page reports what official sources say; it is not medical advice. Medical disclaimer.